Anti-Aging

Exosomes: the next generation of skin regeneration

July 5, 2023

Last month I turned 47—and overall, I’m feeling great about it. I love to read about women feeling their best in their forties and beyond. As we grow into our age we start to feel more comfortable in our skin and that is so freeing! I feel like I have a lot to look forward to over the next decade. That said, I have begun to notice the inevitable changes in my skin that come with aging—the skin laxity and fine lines. In an effort to avoid an unnatural aesthetic that can come from the overuse of injectables, I set out to research the most cutting-edge non-invasive alternatives to botox and filler. Which is why I approached the experts at Greenwich Med Spa to help me think about a plan to age gracefully, without injectables or fillers.

I meet with Saasha at Greenwich Med Spa in Glastonbury CT and she spent over 30 minutes chatting with me about a plan for my skin over the next year. She is an aesthetics expert, having been in the industry for many years. She totally understood my concerns about going needle-free (after a not-so-great experience many years ago). The first service she outlined was a treatment that GMS just started offering. It is called The Generator. This is a procedure that treats facial skin in a short 20-minute session, promising fewer wrinkles and a more lifted appearance over time.

Let’s get into it…

What are exosomes?

Imagine a medical treatment that is so regenerative, cutting-edge, and promising that it has the potential to cure diseases that were once thought incurable. That’s exactly what exosome therapy might offer. By harnessing the power of tiny cellular messengers called exosomes (which are literally how our cells communicate with each other), this revolutionary therapy has the potential to treat a wide range of conditions, from chronic pain and cancer to neurodegenerative, inflammatory, and cardiovascular disorders too. In this blog post, we’ll specifically discussing using exosomes topically to help regenerate skin.


Exosomes are derived from adipose stem cells and contain over 50 growth factors, 30+ collagen types, and 300+ growth factors.

Exosome therapy is a new treatment that is used both medically and for beauty purposes. It involves a cutting-edge cellular regeneration technique that builds upon the success of other proven therapies like stem cell therapy and platelet-rich plasma. Exosomes can be delivered either to skin topically after a laser or micro-needling treatment. By improving cell signaling, reducing inflammation, and promoting cellular regeneration this therapy has shown promise.

At the heart of exosome therapy are exosomes themselves.  Exosomes have been described as “tiny bubbles that are released from cells, especially from stem cells”. They’re also called extracellular vesicles. These “bubbles” are lipid spheres that act as messengers and carry genetic information and critical signaling proteins to be delivered to other cells.

When I visited the aesthetician at GMS for my first treatment, she confirmed that in her experience, exosomes really do have the ability to renew skin.

So, how well does The Generator actually work?

The treatment starts with a Diamond Glow facial. This is similar to a Hydrafacial. It basically is a Microderm treatment to create an open porous environment for the skin to absorb the amazing exosomes. Instead of the next phase of the facial, where seems are introduced to penetrate the skin, exosomes are then manually massaged into the skin. You leave with the exosomes on and do not wash them off until the next morning. According to their website, GMS also provides a vial of exosomes to apply over the ext few days to enhance your treatment.

During the treatment, tiny exosomes are carefully delivered into the skin or scalp through these micro-injuries created to stimulate collagen production and rejuvenate from within.

I felt glowy and refreshed the first day, and with a clearer smoother complexion over the next week. Over the next month fine lines looked softer. See photo for me about a month after treatment. It is to be noted this is best done as a series of 4 treatments.  Each treatment builds on the last.  Patients have to adhere to the treatment protocols and intervals to ensure maximum benefit.

What exactly does that mean for you? 

When it comes to skin, exosomes can be used to stimulate collagen production and cell turnover. This can help reduce the appearance of fine lines and wrinkles, improve skin texture and tone, and even out pigmentation for a smoother, brighter-looking you!

You can also supercharge your treatment by doing microneedling with exosomes to restore and rejuvenate your skin.

In terms of who is a good candidate, anyone who wants to improve skin appearance will likely be pleased with the results.

Before and After

Patients start to see visible improvement even after the first treatment.  However, peak effect is seen 90 days following your treatment. I actually did feel a tightness and lifted feeling immediately following my first treatment.

Aftercare

There’s no aftercare needed, but a series is recommended and “maintenance” sessions may be needed for optimal results over time. After a year, one maintenance treatment is recommended every six months to a year to maintain results. 

Final Takeaway

In conclusion this is a novel and innovative treatment option that utilizes the latest advances in medical science. This treatment provides:

  • Reduction in the appearance of age-related pigment 
  • Visibly makes skin appear firmer and more youthful 
  • Visibly reduces the appearance of fine lines and wrinkles 
  • Hydrates and nourishes skin 
  • Increased collagen production 
  • More radiant and even-toned complexion 
  • Overall brightness and hydration 
  • Reduction in redness and skin irritation 
  • Reduction in pore size and texture

For my own skincare goals—a very natural lifted and tightened look—my review of The Generator treatment is ….. I was honestly surprised at how much I could seethe results immediately, and I love that it’s a needle-free option to naturally build collagen. I’m planning to continue treatments and look forward to seeing cumulative results.

If you are interested in learning more about exosomes and The Generator contact Greenwich Med Spa.

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